Sub-chronic elevation in ambient temperature drives alterations to the sperm epigenome and accelerates early embryonic development in mice
N. A. Trigg, J. E. Schjenken, J. H. Martin, D. A. Skerrett-Byrne, S. P. Smyth, I. R. Bernstein, A. L. Anderson, S. J. Stanger, E. N. A. Simpson, A. Tomar, R. Teperino, C. C. Conine, G. N. De Iuliis, S. D. Roman, E. G. Bromfield, , B. Nixon
This study shows that sub-chronic heat stress alters sperm small non-coding RNA profiles in mice, leading to accelerated embryonic development and fetal weight gain.
bioRxiv · Jul 22, 2024Cell Biology