p38delta genetic ablation protects female mice from anthracycline cardiotoxicity
S. A. George, A. Kiss, S. N. Obaid, A. Venegas, T. Talapatra, C. Wei, T. Efimova, I. R. Efimov
This study shows that deleting p38delta in female mice reduces anthracycline-induced cardiotoxicity by improving cardiac function and autophagy, while p38gamma deletion has no effect.
bioRxiv · Mar 2, 2020Physiology