Author

A. Villegas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

V. Muralidharan· 2 shared A. Conway· 1 shared B. Asady· 1 shared B. Bruton· 1 shared C. F. Brooks· 1 shared D. W. Cobb· 1 shared G. Lew· 1 shared H. Fong· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

V. Muralidharan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A Serum- and Feeder-Free System to Generate CD4 and Regulatory T Cells from Human iPSCs

H. Fong, M. Mendel, J. Jascur, L. Najmi, K. Kim, G. Lew, S. Garimalla, S. Schock, J. Hu, A. Villegas, A. Conway, J. D. Fontenot, S. Zompi

This paper describes a serum- and feeder-free method to generate CD4 and regulatory T cells from human iPSCs, enabling scalable production for therapeutic applications.

bioRxiv · Jul 1, 2023Cell Biology

A druggable oxidative folding pathway in the endoplasmic reticulum of human malaria parasites

D. W. Cobb, H. M. Kudyba, A. Villegas, M. R. Hoopmann, R. Baptista, B. Bruton, M. Krakowiak, R. L. Moritz, V. Muralidharan

This study identifies a druggable oxidative folding pathway in the ER of P. falciparum, showing that PfPDI8 is essential and sensitive to small molecule inhibition.

bioRxiv · May 13, 2020Microbiology

An ER CREC family protein regulates the egress proteolytic cascade in malaria parasites

M. A. Fierro, B. Asady, C. F. Brooks, A. Villegas, S. N. J. Moreno, V. Muralidharan

This study identifies PfERC, an ER-resident CREC family protein, as essential for the proteolytic cascade regulating egress in malaria parasites.

bioRxiv · Jul 31, 2019 · PreprintCell Biology