Rapid and efficient generation of antigen-specific isogenic T cells from cryopreserved blood samples
A. Eerkens, A. Vledder, N. van Rooij, F. Foijer, H. W. Nijman, M. de Bruyn
This study demonstrates an efficient CRISPR/Cas9 protocol for modifying ex vivo human T cells without affecting viability or antigen-specific responses.
bioRxiv · Nov 12, 2021Immunology