ImmunologybioRxiv
Rapid and efficient generation of antigen-specific isogenic T cells from cryopreserved blood samples
A. Eerkens, A. Vledder, N. van Rooij…·M. de Bruyn
This study demonstrates an efficient CRISPR/Cas9 protocol for modifying ex vivo human T cells without affecting viability or antigen-specific responses.
DOI 10.1111/imcb.12538