Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma.
K. M. Makielski, A. L. Sarver, M. S. Henson, K. M. Stuebner, A. Borgatti, L. Suksanpaisan, C. Preusser, A.-F. Tabaran, I. Cornax, M. G. O'Sullivan, A. Chehadeh, D. Groschen, K. Bergsrud, S. Pracht, A. Winter, , S. Naik
This study evaluates neoadjuvant oncolytic virus therapy in dogs with osteosarcoma, finding it safe and associated with increased long-term survivorship and immune gene expression.
bioRxiv · Apr 16, 2023Cancer Biology