The response network of HSP70 defines vulnerabilities in cancer cells with the inhibited proteasome
M. Oron, M. Grochowski, A. Jaiswar, J. Legierska, K. Jastrzebski, M. Nowak-Niezgoda, M. Kolos, W. Kazmierczak, T. Olesinski, M. Lenarcik, M. Cybulska, M. Mikula, A. Zylicz, M. Miaczynska, K. Zettl, , D. Walerych
The paper identifies HSP70 as a vulnerability in cancer cells under proteasome inhibition, showing its role in suppressing drug effects and linking its expression to patient risk.
bioRxiv · Nov 16, 2021Cancer Biology