Impaired iron recycling from erythrocytes is an early iron-dependent hallmark of aging
P. Slusarczyk, P. K. Mandal, G. Zurawska, M. Niklewicz, K. Kumari Chouhan, M. Macias, A. Szybinska, M. Cybulska, O. Krawczyk, S. Herman, M. Mikula, R. Serwa, M. Lenartowicz, W. Pokrzywa, K. Mleczko-Sanecka
This study identifies impaired iron recycling by splenic red pulp macrophages as an early hallmark of aging and shows that reducing dietary iron improves iron turnover in aged mice.
bioRxiv · Jan 16, 2022Physiology