Liver sinusoidal endothelial cells constitute a major route for hemoglobin clearance
G. Zurawska, Z. Sas, A. Jonczy…·K. Mleczko-Sanecka
This study identifies liver sinusoidal endothelial cells as the primary cells responsible for hemoglobin clearance, revealing their role in heme detoxification and iron homeostasis through macropinocytosis and the BMP6-hepcidin axis.