BiochemistryBiochemical JournalPeer-reviewed
Unconventional binding of Calmodulin to CHK2 kinase inhibits catalytic activity
Christopher R. Horne, Tingting Wang, Samuel N. Young…·James M. Murphy
The paper identifies an unconventional mechanism where Ca2+-CaM binds CHK2 kinase to inhibit its activity, contrasting with its typical role in promoting kinase activity.
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