BioengineeringbioRxivPreprint
An Improved Manufacturing Method for Infusible Extracellular Matrix Materials to Enable Efficient Scale-Up, Improved Efficacy, and Clinical Translation
Michael Nguyen, Emma I Zelus, Maria L Karkanitsa…·Karen L. Christman
This paper introduces a new manufacturing method for infusible extracellular matrix (iECM) using depth filtration and tangential flow filtration (DF-TFF) to improve production efficiency, concentration, and compliance with cGMP standards.
DOI 10.64898/2026.10.29.762959