Author

Ai Lin

Chinese Academy of Medical Sciences & Peking Union Medical College

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Eric J. WagneriD· 2 shared Nathan D. ElrodiD· 2 shared Ping JiiD· 2 shared Aaron C. GoldstrohmiD· 1 shared Afaf SalibaiD· 1 shared Alexander B. SaltzmaniD· 1 shared Anna MalovannayaiD· 1 shared Bhoomi BhattiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Eric J. WagnerORCID

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2 papers

Recent·Most cited

Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome

Isioma Enwerem-Lackland, Nathan D. Elrod, Chung-Te Chang, Ai Lin, Ping Ji, Jennifer A. Bohn, Yevgen Levdansky, Eric J. Wagner, Eugene Valkov, Aaron C. Goldstrohm

This study identifies how PUM1 and PUM2 regulate gene expression by interacting with the CCR4-NOT complex and DCP2 to repress mRNA decay.

RNA · Jan 4, 2021Peer-reviewedMolecular Biology

Partial loss of CFIm25 causes aberrant alternative polyadenylation and learning deficits

Callison E Alcott, Hari Krishna Yalamanchili, Ping Ji, Meike E. van der Heijden, Alexander B. Saltzman, Nathan D. Elrod, Ai Lin, Mei Leng, Bhoomi Bhatt, Shuang Hao, Qi Wang, Afaf Saliba, Jianrong Tang, Anna Malovannaya, Eric J. Wagner, , Huda Yahya Zoghbi

The paper shows that partial loss of CFIm25, a protein regulated by NUDT21, causes learning deficits and molecular changes in neurons.

eLife · Apr 22, 2020Peer-reviewedGenomics