BiochemistryProteins Structure Function and BioinformaticsPeer-reviewed
Predicting pose distribution of protein domains connected by flexible linkers is an unsolved problem
Allen C. McBride, Feng Yu, Edward H. Cheng…·Bruce Randall Donald
The paper evaluates computational methods for predicting interdomain pose distributions in D-L-D proteins using NMR and SAXS data, finding none accurately match experimental results.
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