Molecular BiologyBMC Genomic DataPeer-reviewed
The amniote-conserved DNA-binding domain of CGGBP1 restricts cytosine methylation of transcription factor binding sites in proximal promoters to regulate gene expression
Ishani Morbia, Praveen Kumar Issac, Aditi Lakshmi Satish…·Umashankar Singh
This study shows CGGBP1's DNA-binding domain prevents cytosine methylation at transcription factor binding sites in promoters, regulating gene expression and evolving as a key mechanism in vertebrates.