Author

Alexander Froese

University Medical Center Hamburg-Eppendorf;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

Bing Qi· 1 shared Cristina E. Molina· 1 shared David Revuelta· 1 shared Greta Boeer· 1 shared Hariharan Subramanian· 1 shared Heimo Ehmke· 1 shared Jose L. Sanchez-Alonso· 1 shared Julia Gorelik· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Bing Qi

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1 paper

Recent·Most cited

Submembrane geography dictates GPCR signalling compartmentation and physiological function

Alexander Froese, Bing Qi, Miao Feng, Greta Boeer, Karoline Morhenn, Svenja Kupsch, Xing Sun, Hariharan Subramanian, Jose L. Sanchez-Alonso, Roman Medvedev, Peter T. Wright, Mart Gallego, David Revuelta, Nadja I. Beck, Cristina E. Molina, , Viacheslav Nikolaev

This study shows that GPCR signaling varies based on submembrane location, with different functional outcomes in cardiomyocytes, and introduces submembrane-specific beta-blockers that target specific nanodomains.

bioRxiv · Nov 3, 2026 · PreprintPharmacology & Toxicology