Author

David Revuelta

HafenCity University Hamburg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Organism:mouse· 2 Approach:experimental assay· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam Linekar· 1 shared Alexander Froese· 1 shared Andreas KoschinskiiD· 1 shared Bing Qi· 1 shared Christopher N. ToepferiD· 1 shared Connor M. BlairiD· 1 shared Craig A. LygateiD· 1 shared Cristina E. Molina· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

Adam Linekar

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2 papers

Recent·Most cited

Submembrane geography dictates GPCR signalling compartmentation and physiological function

Alexander Froese, Bing Qi, Miao Feng, Greta Boeer, Karoline Morhenn, Svenja Kupsch, Xing Sun, Hariharan Subramanian, Jose L. Sanchez-Alonso, Roman Medvedev, Peter T. Wright, Mart Gallego, David Revuelta, Nadja I. Beck, Cristina E. Molina, , Viacheslav Nikolaev

This study shows that GPCR signaling varies based on submembrane location, with different functional outcomes in cardiomyocytes, and introduces submembrane-specific beta-blockers that target specific nanodomains.

bioRxiv · Nov 3, 2026 · PreprintPharmacology & Toxicology

Precision Targeting of Troponin I Phosphorylation Prevents Diastolic Dysfunction while Preserving Systolic Performance

Ying‐Chi Chao, Debra J. McAndrew, David Revuelta, Rahul Yadav, Wan-Hua Hong, Jianshu Hu, Milda Folkmanaite, Edoardo Valli, Mariana Gee Olmedilla, Andreas Koschinski, Nicoletta Concetta Surdo, Jakub Tomek, Diederik W.D. Kuster, Helen V. Edwards, Connor M. Blair, , Manuela Zaccolo

This paper identifies a nanodomain mechanism regulating troponin I phosphorylation and demonstrates a peptide that selectively enhances relaxation without compromising systolic function in heart failure.

bioRxiv · Nov 18, 2025 · PreprintCell Biology