Author

Alexander Schug

Karlsruhe Institute of Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Biophysics· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:protein sequence· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sharifian· 1 shared Benjamin MattesiD· 1 shared Bernadett Bösze· 1 shared Claude SinneriD· 1 shared Hervé Jacquier· 1 shared Joachim WittbrodtiD· 1 shared Kathrin Stricker· 1 shared Martin WeigtiD· 1 shared

Activity by Year

2015-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiophysics

A. Sharifian

Author profile →

3 papers

Recent·Most cited

Dynamical Fingerprints of Rare-Event Transitions from Transition Corridors

A. Sharifian, Alexander Schug

The paper introduces a method to identify key players in rare conformational transitions of proteins by analyzing transition corridors and testing their impact through computational and mutational approaches.

bioRxiv · Nov 10, 2026 · PreprintBiophysics

Pcdh18a-positive tip cells instruct notochord formation in zebrafish

Bernadett Bösze, Benjamin Mattes, Claude Sinner, Kathrin Stricker, Victor Gourain, Thomas Thumberger, Sham Tlili, Sabrina Weber, Joachim Wittbrodt, Timothy E. Saunders, Uwe Strähle, Alexander Schug, Steffen Scholpp

The paper identifies Pcdh18a-positive tip cells that guide notochord formation in zebrafish through migration and signaling.

Histochemistry and Cell Biology · Jun 1, 2020Peer-reviewedDevelopmental Biology

Coevolutionary landscape inference and the context-dependence of mutations in beta-lactamase TEM-1

Matteo Figliuzzi, Hervé Jacquier, Alexander Schug, Olivier Tenaillon, Martin Weigt

The paper develops a method to infer mutational landscapes and assesses context-dependent mutation effects in beta-lactamase TEM-1, improving explanatory power by 40% over methods ignoring epistasis.

Molecular Biology and Evolution · Oct 6, 2015Peer-reviewedBioinformatics