The panC-encoded pantothenate synthetase to tackle carbapenem-resistant OprD Pseudomonas aeruginosa mutant revealed through Tn-Seq
Cléophée Van Maele, Ségolène Caboche, Marin Moutel…·Thomas Guillard
This study identifies panC as a therapeutic target in OprD-deficient Pseudomonas aeruginosa by showing its role in growth and virulence through transposon sequencing and CRISPRi.