GenomicsbioRxivPreprint
Functional characterization of thousands of type 2 diabetes-associated and chromatin-modulating variants under steady state and endoplasmic reticulum stress
Shubham Khetan, Susan Kales, Romy Kursawe…·Michael L. Stitzel
The paper identifies functional β cell transcriptional variants from T2D GWAS SNPs using MPRA, showing strong correlation with chromatin accessibility and revealing regulatory features under stress conditions.