Author

Alisa Bruce

Children's National

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:rat· 1

Frequent Co-Authors

Devon GuerrelliiD· 2 shared Nikki Gillum PosnackiD· 2 shared Allison Freeman· 1 shared Anika Haski· 1 shared Jenna Pressman· 1 shared Kathleen McLean· 1 shared Luther SwiftiD· 1 shared Manan Desai· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

Devon GuerrelliORCID

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2 papers

Recent·Most cited

Functional Assessment and Extended Culture of Human Pediatric Cardiac Tissue Slices for Preclinical Testing

Devon Guerrelli, Kathleen McLean, Allison Freeman, Jenna Pressman, Alisa Bruce, Manan Desai, Yves d'Udekem, Nikki Posnack

This study develops a method to culture human pediatric cardiac tissue slices for extended periods, enabling functional and pharmacological testing of cardiac physiology.

bioRxiv · Nov 5, 2026 · PreprintPhysiology

Chamber-Specific Transcriptomic Insight into Cardiac Development using Guinea Pig and Human Heart Tissue

Shatha Salameh, Devon Guerrelli, Luther Swift, Anika Haski, Alisa Bruce, Manan H. Desai, Yves d’Udekem, Nikki Gillum Posnack

This study characterizes age- and chamber-specific gene expression patterns in guinea pig and human hearts, identifying conserved maturation markers to support guinea pigs as a preclinical model for pediatric cardiology.

Physiological Genomics · Nov 6, 2025Peer-reviewedGenomics