Devon Guerrelli

This study develops a method to culture human pediatric cardiac tissue slices for extended periods, enabling functional and pharmacological testing of cardiac physiology.

This study integrates patient-specific heart rates into computational models of pediatric atrial cardiomyocytes to show how developmental changes and pacing rates jointly influence electrophysiological biomarkers.

This study characterizes age- and chamber-specific gene expression patterns in guinea pig and human hearts, identifying conserved maturation markers to support guinea pigs as a preclinical model for pediatric cardiology.

This study analyzes age-dependent gene expression and electrophysiological changes in pediatric patients with congenital heart disease using computational modeling.

This study examines how temporal changes and experimental parameters affect the electrophysiology of hiPSC-CMs, highlighting variability in beating rate, field potential duration, and drug responsiveness.