Author

Alistair Wilkinson

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Christopher J. TapeiD· 3 shared Smita KrishnaswamyiD· 3 shared Aurélie DobriciD· 2 shared Petra VlckovaiD· 2 shared Rhianna O’SullivaniD· 2 shared Shauna CrampsieiD· 2 shared A McCullochiD· 1 shared Ashley Campbell· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCancer Biology

Christopher J. TapeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GeoSinkhorn Flow: Geometry-Aware Flow Matching for Perturbation-Conditioned Dynamics in Single cell Data Phenoscapes

Ke Xu, Alistair Wilkinson, Ni Shuang, Guillaume Huguet, Gerstein Mark, Guy Wolf, Christopher J. Tape, Smita Krishnaswamy

GeoSinkhorn Flow converts static phenoscapes into dynamic ones by learning perturbation-conditioned transport trajectories that respect the phenoscape's geometry and generalize to unseen conditions.

bioRxiv · Oct 22, 2026 · PreprintBioinformatics

Epithelial Stem Cell Fate Determines Chemoradiotherapy Response in Rectal Cancer

N. Li, Fiza Ishaqwala, Thomas A. Wright, Alistair Wilkinson, Petra Vlckova, Katherine E. Trevers, Rhianna O’Sullivan, Shauna Crampsie, Ewa Basiarz, Sierra Vanderkamp, A McCulloch, Aurélie Dobric, Smita Krishnaswamy, Bart Vanhaesebroeck, Campbell S.D. Roxburgh, , Christopher J. Tape

This study identifies that epithelial stem cell fate, not DNA damage, determines chemoradiotherapy response in rectal cancer by analyzing patient-derived organoids and using SPARTA to validate findings.

bioRxiv · Jul 15, 2026 · PreprintCancer Biology

Stromal Prostaglandin is a Dominant Spatial Regulator of Cell-fate Plasticity in Colorectal Cancer

Corinne Molyneux, Rhianna O’Sullivan, Eoghan J. Mulholland-Illingworth, Joshua W. Moore, Nick Li, Petra Vlckova, Raheleh Amirkhah, Aurélie Dobric, Shauna Crampsie, Alistair Wilkinson, Jack Langley, Marta Labarquilla Alonso, Ashley Campbell, Jeroen Claus, Smita Krishnaswamy, , Christopher J. Tape

This study identifies stromal prostaglandin E2 as a key regulator of cell-fate plasticity in colorectal cancer, showing it converts chemosensitive stem cells into chemorefractory, prometastatic cells.

bioRxiv · Jun 18, 2026 · PreprintCancer Biology