Author

Jack Langley

University College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alistair Wilkinson· 1 shared Ashley Campbell· 1 shared Aurélie DobriciD· 1 shared Christopher J. TapeiD· 1 shared Corinne MolyneuxiD· 1 shared Eoghan J. Mulholland-IllingworthiD· 1 shared Jeroen ClausiD· 1 shared Joshua W. MooreiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alistair Wilkinson

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Stromal Prostaglandin is a Dominant Spatial Regulator of Cell-fate Plasticity in Colorectal Cancer

Corinne Molyneux, Rhianna O’Sullivan, Eoghan J. Mulholland-Illingworth, Joshua W. Moore, Nick Li, Petra Vlckova, Raheleh Amirkhah, Aurélie Dobric, Shauna Crampsie, Alistair Wilkinson, Jack Langley, Marta Labarquilla Alonso, Ashley Campbell, Jeroen Claus, Smita Krishnaswamy, , Christopher J. Tape

This study identifies stromal prostaglandin E2 as a key regulator of cell-fate plasticity in colorectal cancer, showing it converts chemosensitive stem cells into chemorefractory, prometastatic cells.

bioRxiv · Jun 18, 2026 · PreprintCancer Biology