BiophysicsbioRxiv
Intrinsically disordered regions in the transcription factor MYC:MAX modulate DNA binding via intramolecular interactions
Stefan Schütz, Christian Bergsdorf, Sandra Hänni-Holzinger…·Wolfgang Jahnke
This study identifies intramolecular interactions between intrinsically disordered regions and the DNA binding domain of MYC:MAX, showing they compete with DNA binding and slow complex formation.
DOI 10.1021/acs.biochem.3c00608