BiochemistrybioRxiv
Structural and mechanistic insights into disease-associated endolysosomal exonucleases PLD3 and PLD4
Meng Yuan, Linghang Peng, Deli Huang…·David Nemazee
This study reports the structures and mechanistic insights of PLD3 and PLD4, revealing their exonuclease activity, phosphatase function, and disease relevance.
DOI 10.1016/j.str.2024.02.019