MicrobiologybioRxivPreprint
RABV L protein plays a role in immune escape through its methyltransferase activity
Marilys Castet, Wahiba Aouadi, Lauriane Kergoat…·Florence Larrous
This study shows that the K-D-K-E motif in RABV L protein's methyltransferase domain is crucial for immune evasion by altering viral and host RNA methylation, increasing sensitivity to interferon, and reducing pathogenicity.
DOI 10.1101/2025.09.12.675814