BiophysicsbioRxivPreprint
Outer Pore Collapse as a Potential Mechanism of Partial Loss of Pain in Nav1.7 M899I
Vishal Sudha Bhagavath Eswaran, Estefania Torres-Ortiz, Petra A. I. Hautvast…·Angelika Lampert
The paper investigates the M899I variant in Nav1.7, showing it causes pore collapse, leading to loss of sodium currents and pain insensitivity.
DOI 10.64898/2026.08.18.745213