GeneticsbioRxivPreprint
Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy
Sattar Khoshkhoo, Mingyun Bae, Yilan Wang…·Christopher A. Walsh
This study identifies somatic Ras-MAPK pathway variants in hippocampal tissue from patients with drug-resistant epilepsy, showing their association with clonal competition and worse surgical outcomes.
5 citations