Cancer BiologybioRxivPreprint
Spatial architecture of CD8+ T cells and DC subsets is critical for the response to immune checkpoint inhibitors in melanoma
Elisa Gobbini, Margaux Hubert, Anne-Claire Doffin…·Jenny Valladeau-Guilemond
This study examines the spatial organization of dendritic cell (DC) subsets and their interactions with CD8+ T cells in melanoma patients, finding that proximity between cDC1 and CD8+ T cells correlates with response to immune checkpoint inhibitors.
DOI 10.1101/2024.02.06.579128