Anatoly Vasilyev

The paper introduces a method to quantify diverse perturbation responses and discover novel biological insights in single-cell perturbation datasets.

This study identifies and characterizes prokaryotic Argonautes (pAgos) as programmable endonucleases, showing their ability to cleave DNA in vitro with guide RNA/DNA and potential for gene editing.

Knomics-Biota provides a web-based tool for exploratory analysis of human gut metagenomic data, enabling users to generate reports and visualize microbiota composition in relation to experimental factors and public datasets.