ImmunologybioRxivPreprint
Tricked by Edge Cases: Can Current Approaches Lead to Accurate Prediction of T-Cell Specificity with Machine Learning?
Martin Culka, Jonathan Desponds, Jeanne Cheung…·Darya Yu. Orlova
This paper evaluates machine learning approaches for predicting T-cell receptor specificity, highlighting limitations in current data and methods, and proposes a new framework integrating biophysical measurements.