Systems BiologybioRxivPreprint
A model of Rtc-regulated RNA repair reveals heterogeneous responses to ribosome-targeting antibiotics and suggests molecular targets to potentiate their effects
Hollie J. Hindley, Zechuan Gong, Shafagh Moradian…·Andrea Y. Weiße
The paper develops a computational model of Rtc-regulated RNA repair in E. coli, revealing cell-to-cell heterogeneity in antibiotic resistance and suggesting targets to enhance antibiotic efficacy.
DOI 10.1101/2024.05.20.594959