GenomicsbioRxivPreprint
Pathological LSD1 mutations repress enhancer-mediated gene regulatory networks in early differentiation
Daria Bunina, Pierre‐Luc Germain, Alejandro Tobon…·Kyung‐Min Noh
The paper identifies gene regulatory network disruptions caused by LSD1 mutations in early differentiation, showing impaired transcription factor activity and potential therapeutic targets through HDAC inhibition.
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