Motor protein disruption critically alters organelle trafficking, NMJ formation, and excitation contraction coupling.
Himanshu Bansal, Tadros A. Hana, Andrew H. Michael…·Kiel G. Ormerod
This study identifies kinesin 1 and 3 as critical regulators of organelle trafficking in motor neurons, leading to morphological and functional disruptions in neuromuscular junctions and behavior.