Author

Andrew Mazzanti

Mount Sinai Hospital

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Brandon ChoiD· 1 shared Giacomo FurlaniD· 1 shared Kirti Mittal· 1 shared Linda Z. PenniD· 1 shared Mélissa Shen· 1 shared Miguel Ramalho‐SantosiD· 1 shared Peter LiniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Brandon ChoORCID

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1 paper

Recent·Most cited

Cancer BiologyOncogenePeer-reviewedMar 7, 2026

CHD1 is a synthetic lethal vulnerability in MYC-driven breast cancer

Brandon Cho, Giacomo Furlan, Peter Lin…·Miguel Ramalho‐Santos

The paper identifies CHD1 as a synthetic lethal target in MYC-driven breast cancer, showing that its loss suppresses tumor growth and induces cell death in MYC-overexpressing models.

DOI 10.1038/s41388-026-03709-9

humanbulk RNA-seq

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