Cell BiologybioRxivPreprint
Small molecule inhibitors of G9a reactivate the maternal PWS genes in Prader-Willi-Syndrome patient derived neural stem cells and differentiated neurons
Hao Wu, Carrie Ng, Vivian Villegas…·Owen Wallace
This study shows that G9a inhibitors reactivate maternal PWS genes in patient-derived neural cells and induce downstream PWS-related genes without altering DNA methylation at the PWS-IC.
DOI 10.1101/640938