BiochemistryNucleic Acids ResearchPeer-reviewed
Uncovering nick DNA binding by LIG1 at the single-molecule level
Surajit Chatterjee, Loïc Chaubet, Aafke A. van den Berg…·Melike Çağlayan
This study investigates how LIG1 binds to nick DNA at the single-molecule level, revealing specific and non-specific binding dynamics and the role of the N-terminal region in nick search.