NeuroscienceAlzheimer s & DementiaPeer-reviewed
Cellular dynamics across aged human brains uncover a multicellular cascade leading to Alzheimer's disease
Gilad Sahar Green, Masashi Fujita, Hyun-Sik Yang…·Philip L. De Jager
The paper identifies two distinct aging trajectories in the human brain linked to Alzheimer's disease or alternative aging, using single-nucleus RNA-seq data and causal modeling.