Molecular BiologybioRxivPreprint
Endothelial CLK2 as a therapeutic target for acute radiation syndrome
Ryan R. Posey, Aliçan Özkan, Yuncheng Man…·Donald E. Ingber
This study identifies CLK2 as a therapeutic target for acute radiation syndrome by showing CLK2 inhibitors protect endothelial cells and reverse radiation injury in human organ models.
DOI 10.1101/2025.11.05.686891