Developmental BiologybioRxivPreprint
BAP1 deubiquitinase is a potent repressor of fetal hemoglobin biosynthesis
Lei Yu, Natee Jearawiriyapaisarn, Mary P. Lee…·James Douglas Engel
The paper identifies BAP1 as a key repressor of fetal hemoglobin biosynthesis by maintaining NCoR1 at the β-globin locus and shows its inhibition increases γ-globin synthesis.
DOI 10.1101/346619