Molecular BiologyEMBO ReportsPeer-reviewed
ULK-mediated phosphorylation of ATG16L1 promotes xenophagy, but destabilizes the ATG16L1 Crohn’s mutant
Reham M. Alsaadi, Truc T. Losier, Wensheng Tian…·Ryan Charles Russell
This study shows ULK1 phosphorylates ATG16L1, enhancing wildtype function but destabilizing the Crohn’s disease-associated mutant, thereby affecting xenophagy.
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