BiophysicsSmall MethodsPeer-reviewed
Fluorescence Characterization of Extracellular Vesicles using Single-Molecule Confocal Microscopy
Tianxiao Zhao, Noelia Pelegrina‐Hidalgo, Daniel C. Edwards…·Mathew H. Horrocks
This study develops a method to detect and quantify extracellular vesicles using fluorescent antibodies and single-molecule confocal microscopy, achieving femtomolar sensitivity without purification.