Author

Apurva Srivastava

Frederick National Laboratory for Cancer Research

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alana L. WelmiD· 1 shared Bryan Welm· 1 shared Chieh-Hsiang Yang· 1 shared Elisabeth Brown· 1 shared Emilio Cortes Sanchez· 1 shared Hui YangiD· 1 shared Jaime Fornetti· 1 shared Paige Jensen· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alana L. WelmORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintOct 28, 2026

Response to SMAC mimetics in patient-derived models of triple-negative breast cancer relies on RIPK1 activation

Elisabeth Brown, Paige Jensen, Chieh-Hsiang Yang…·Alana L. Welm

This study identifies RIPK1 activation as a key determinant of response to SMAC mimetics in TNBC, showing that resistance is linked to impaired RIPK1 autophosphorylation and HOIP overexpression.

DOI 10.64898/2026.10.26.761582

humanbulk RNA-seq

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