BiochemistrybioRxivPreprint
The B. subtilis replicative polymerases bind the sliding clamp with different strengths to tune replication processivity and fidelity
Luke G. O’Neal, Madeline N. Drucker, Ngoc Khanh Lai…·Elizabeth S. Thrall
This study investigates how the sliding clamp interacts with two replicative polymerases in B. subtilis, showing that PolC-DnaN binding is essential for replication while DnaE-DnaN interaction is dispensable but affects mutagenesis.
DOI 10.1101/2025.03.10.642433