Systems BiologyJournal of the American Chemical SocietyPeer-reviewed
The Holdup Multiplex, an assay for high-throughput measurement of protein-ligand affinity constants using a mass-spectrometry readout
François Delalande, Søren Østergaard, Gergő Gógl…·Élodie Monsellier
The paper introduces a high-throughput mass-spectrometry-based assay to measure protein-ligand affinity constants, demonstrating its application to 14-3-3 isoforms and phosphopeptides.
20 citations