Cell BiologybioRxivPreprint
Mechanisms of Pathogenicity of Hypertrophic Cardiomyopathy-Associated Troponin T (TNNT2) Variant R278C+/- During Development
Sanam Shafaattalab, Alison Yueh Li, Farah Jayousi…·Glen F. Tibbits
This study investigates the pathogenic mechanisms of the TNNT2 R278C+/- variant in cardiomyocytes using proteomics and functional assays, revealing its impact on cardiac function and arrhythmia.
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