Oblique Line Scan Illumination Enables Expansive, Accurate and Sensitive Single Protein Measurements in Solution and in Living Cells
A. Driouchi, M. Bretan, B. J. Davis, A. B. Heckert, M. Seeger, M. Bradley Silva, W. S. Forrest, J. Hsiung, J. Tan, H. Yang, D. T. McSwiggen, L. Song, A. Sule, B. Abaie, B. Conroy, , D. J. Anderson
This paper introduces Oblique Line Scan (OLS) illumination to enhance single-molecule tracking in living cells and solution, enabling high-throughput and sensitive protein dynamics measurements.
bioRxiv · Dec 21, 2023Biophysics