LRRK2 regulates the activation of the unfolded protein response and antigen presentation in macrophages during inflammation
A. M. Fahmy, T. Cannon, C. H. Paredes, A. Ahmadi, Y. Z. Xu, B. Barette, M. Ibrahim, J. Lanoix, G. Arango-Duque, E. Schurr, E. Chevet, P. Thibault, S. Gruenheid, H. McBride, M. Desjardins
This study identifies LRRK2 as a regulator of the unfolded protein response and antigen presentation in macrophages during inflammation, linking it to immune response mechanisms.
bioRxiv · Jun 14, 2023 · PreprintImmunology