Structural and functional vascular dysfunction within brain metastases is linked to pembrolizumab inefficacy
A. E. Kim, K. W. Lou, A. Giobbie-Hurder, K. Chang, M. Gidwani, K. Hoebel, J. Patel, M. Cleveland, P. Singh, C. Bridge, S. R. Ahmed, B. Bearce, W. Liu, E. Fuster-Garcia, E. Lee, , E. R. Gerstner
This study links structural and functional vascular dysfunction in brain metastases to pembrolizumab resistance by analyzing perfusion MRI data from 44 patients.
bioRxiv · Aug 25, 2023 · PreprintCancer Biology