Mena regulates the LINC complex to control actin-nuclear lamina associations, trans-nuclear membrane signalling and cancer gene expression
F. Li Mow Chee, B. Beernaert, A. E. P. Loftus, Y. Kumar, B. G. C. Griffith, J. C. Wills, A. P. Wheeler, J. D. Armstrong, M. Parsons, I. M. Leigh, C. M. Proby, A. von Kriegsheim, W. A. Bickmore, M. C. Frame, A. Byron
This study identifies Mena's role in regulating the LINC complex and nuclear architecture, linking it to cancer gene expression through nuclear membrane signaling.
bioRxiv · Aug 31, 2021 · PreprintCell Biology